Matthew Stafford threw four touchdown passes and the Los Angeles Rams beat the New York Giants 28–6 on Monday night, Sept. 21, at SoFi Stadium in Inglewood, California, Reuters and an Associated Press account carried by CBS Sports reported.

Stafford completed 22 of 31 passes for 327 yards with one interception. Davante Adams caught eight passes for 195 yards and two touchdowns (31 and 11 yards). Kyren Williams and Terrance Ferguson also scored receiving touchdowns, Reuters said. Los Angeles improved to 1–1 after a 27–7 Week 1 loss to San Francisco in Australia.

Giants quarterback Jaxson Dart left on the opening series with a left knee injury after a hit from Byron Young and Josaiah Stewart. X-rays were negative; NFL Network reported an apparent MCL sprain, and Giants coach John Harbaugh said that description was “in the neighborhood,” according to Reuters and AP/CBS. Jameis Winston replaced Dart and went 11 of 27 for 111 yards with an interception. New York managed two Dominic Zvada field goals.

AP/CBS said the Rams outgained the Giants 481–182 and that Aaron Donald returned for his first NFL game action in 32 months, totaling three tackles. Rams receiver Puka Nacua (hip) missed the game; AP/CBS also said Myles Garrett was out. Malik Nabers injured a shoulder but returned and finished with one catch for 1 yard, Reuters reported.

Career milestone tallies for Stafford’s touchdown ranking differ slightly between wire accounts and are noted in speculation; the four-TD game performance itself is consistent across sources.